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Home - Products - Membrane Transporter/Ion Channel - BCRP - Brevianamide F

Brevianamide F

CAS No. 38136-70-8

Brevianamide F( Cyclo(L-Pro-L-Trp )

Catalog No. M14319 CAS No. 38136-70-8

A naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 45 In Stock
5MG 81 In Stock
10MG 122 In Stock
25MG 235 In Stock
50MG 402 In Stock
100MG 592 In Stock
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Biological Information

  • Product Name
    Brevianamide F
  • Note
    Research use only, not for human use.
  • Brief Description
    A naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.
  • Description
    A naturally occurring 2,5-diketopiperazine that possess interesting breast cancer resistance protein (BCRP) inhibitory activity.; also shows agonism towards Ca(2+)-channel activity at 100 uM, and has potentiation for use in the treatment of cardiovascular dysfunction.
  • In Vitro
    Brevianamide F shows moderate activity against both MSSA and MRSA.
  • In Vivo
    ——
  • Synonyms
    Cyclo(L-Pro-L-Trp
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    BCRP
  • Recptor
    Others
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    38136-70-8
  • Formula Weight
    283.3251
  • Molecular Formula
    C16H17N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    C1CC2C(=O)NC(C(=O)N2C1)CC3=CNC4=CC=CC=C43
  • Chemical Name
    Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1H-indol-3-ylmethyl)-, (3S,8aS)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jamie H, et al. J Pharm Pharmacol. 2002 Dec;54(12):1659-65. 2. Wauters I, et al. J Org Chem. 2015 Aug 21;80(16):8046-54. 3. Wollinsky B, et al. Org Biomol Chem. 2012 Dec 14;10(46):9262-70.
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